This isn't Cushing's-specific, but MANY of us have Cushing's Disease which is caused by pituitary tumors...and tumors are apparently the #1 cause of adult-onset Growth Hormone Deficiency.  We Cushing's patients have those tumors surgically removed, which surgery also can cause a loss of growth hormone production (double whammy, I say), so this is a very appropriate subject for Cushing's Patients to be aware of.  There is a lot of overlap in the symptomology as well, so AGHD needs to be ruled out as the initial cause of symptoms when being diagnosed as well as when a recurrence might be suspected.

So, today I received the Magic Foundation's Friday email which contained an amazing article with LOTS of good information related to Adult Growth Hormone Deficiency and it's treatment (replacement injections).  This article goes through changes to different body systems (metabolism, muscle, bone, skin, body fat, etc) due to AGHD, and then how those things have been affected by GH replacement therapy.  Like I said, there is a TON of interesting information here, but what I found really interesting was how some changes were immediate (happening within days or weeks), some changes didn't really take effect until 3 or 6 months of continuous treatment (and some of those seeing continued improvement up to 3 years later as well), and then there were other more negative changes that happened up-front but returned to normal as your body adjusted over time.  Click on the title below to read for yourself:

Growth Hormone Deficiency in Adulthood and the Effects of Growth Hormone Replacement: A Review